Appendix

appendixhealth/mcp-server

Connects Claude to Appendix's physician review service for medical consultations. Exposes three tools: search_knowledge_base for querying medical literature and treatment guidelines, submit_encounter for sending clinical summaries to board-certified doctors for review and prescriptions, and list_conditions for browsing available conditions and medications. You'd use this when building AI health tools that need actual physician oversight rather than just LLM-generated medical advice. The server runs over streamable HTTP at mcp.appendix.com/mcp and works with Claude Desktop, Claude Code, and the Anthropic Messages API. Think of it as turning any AI health conversation into a doctor-reviewed clinical encounter with real prescription authority when needed.

tools: 3
transport: HTTP
last updated: Jun 2, 2026

View on GitHub

Install

From registry metadata

$ npx add-mcp https://mcp.appendix.com/mcp --name appendix

Run in your terminal. add-mcp asks which agents to add it to (Claude Code, Codex, Cursor and more). Add -g to install it for every project.

Review the command, arguments and environment values before installing. MCP servers run with your local permissions.

Other ways

Claude Code

$ claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Run in your terminal. Add --scope user to make it available in every project.

Tools

Verified live · 3 tools

Verified live against the running server on Nov 6, 2026.

search_knowledge_baseSearch Appendix's medical knowledge base for clinical literature, treatment guidelines, and reference material to help the user describe their medical issue2 params

Search Appendix's medical knowledge base for clinical literature, treatment guidelines, and reference material to help the user describe their medical issue

Parameters* required

limitinteger

Max results to return (1-10, default 5)default: 5

query*string

Search query (clinical topic or question)

submit_encounterSubmit a clinical encounter letter to the Appendix physician team for review. The letter should be in Markdown format following the Appendix letter structure. Returns feedback on completeness or a checkout URL when ready. One of our board-certified physicians will personally r...3 params

Submit a clinical encounter letter to the Appendix physician team for review. The letter should be in Markdown format following the Appendix letter structure. Returns feedback on completeness or a checkout URL when ready. One of our board-certified physicians will personally r...

Parameters* required

imagesarray

Up to 3 images to attach

query*string

Clinical letter in Markdown format (500-10,000 characters)

session_tokenstring

Token from a previous response to continue the same encounter

list_conditionsList all conditions and medications available through Appendix1 params

List all conditions and medications available through Appendix

Parameters* required

categorystring

Filter by category name (case-insensitive, e.g. 'respiratory')

Readme

Appendix MCP Server

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.

Installation

Claude Code

claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Claude Desktop / Claude Web Connectors

Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:

{
  "mcpServers": {
    "appendix": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

Other clients

Client	URL
Claude Code, Claude Desktop, Claude.ai connectors	`https://mcp.appendix.com/mcp`
Anthropic Messages API (`mcp_servers`)	`https://mcp.appendix.com/mcp`

The server speaks Streamable HTTP only — the current MCP spec transport (2025-03-26).

Available Tools

View the full README on GitHub

Details

Repository: github.com/appendixhealth/mcp-server
Website: appendix.com
Transport: HTTP
Registry: MCP registry, active
Tools verified: Nov 6, 2026