
Claidex MCP
Connects Claude to Claidex's failure intelligence database covering terminated clinical trials across oncology, neurology, and immunology. You get programmatic access to their Claims, which are sourced post-mortems tracing failed drug programs from original hypothesis through preclinical evidence to the mechanistic breakdown of why trials stopped. Useful when you're doing translational research, evaluating target validation, or need to surface why a specific pathway or mechanism didn't pan out in humans. The platform tracks over hundreds of terminated trials with full source citations back to primary literature. Reach for this when you need more than ClinicalTrials.gov entries and want the mechanistic context that rarely makes it into published papers.
- tools
- 24
- auth
- Secret needed
- transport
- STDIO, HTTP
- env vars
- 2
- last updated
- May 24, 2026
Install
From registry metadata$ npx add-mcp https://app.claidex.com/api/mcp --name failure-intelligence --header 'Authorization: Bearer ${API_TOKEN}'Run in your terminal. add-mcp asks which agents to add it to, then asks for each value it needs. Add -g to install it for every project.
Review the command, arguments and environment values before installing. MCP servers run with your local permissions.
Other ways
Claude Code
$ claude mcp add --transport http failure-intelligence https://app.claidex.com/api/mcp --header 'Authorization: YOUR_AUTHORIZATION'Run in your terminal. Add --scope user to make it available in every project.
Tools
Verified live · 24 toolsVerified live against the running server on Nov 6, 2026.
claidex_capabilitiesReturn the Claidex MCP feature map, configured storage/model providers, safety controls, resources, prompts, and tool counts.
Return the Claidex MCP feature map, configured storage/model providers, safety controls, resources, prompts, and tool counts.
No parameters. Call it with no arguments.
claidex_claim_risk_matrixSearch claims and summarize MRS bands, trial phases, failure archetypes, and high-risk programs for rapid diligence.2 params
Search claims and summarize MRS bands, trial phases, failure archetypes, and high-risk programs for rapid diligence.
limit*integerquery*stringclaidex_health_snapshotReturn Sentinel metrics, coverage, graph counts, recent automation runs, MRS bands, and preprint-watch summaries.
Return Sentinel metrics, coverage, graph counts, recent automation runs, MRS bands, and preprint-watch summaries.
No parameters. Call it with no arguments.
claidex_research_promptCompose a rigorous, reusable investigation prompt that tells an MCP client which Claidex tools and resources to use.4 params
Compose a rigorous, reusable investigation prompt that tells an MCP client which Claidex tools and resources to use.
diseasestringobjective*stringrisk_tolerance*stringlow · medium · highdefault: mediumtarget_genestringclaidex_tool_catalogReturn the complete MCP tool catalog, optionally including full input schemas and filtering native versus agent-backed tools.2 params
Return the complete MCP tool catalog, optionally including full input schemas and filtering native versus agent-backed tools.
include_schemas*booleansource*stringall · claidex-agent · mcp-nativedefault: allconsult_specialist_modelAsk a specialist Gateway model for code, database/tool-calling, statistics, literature, preprint, or mechanistic synthesis support. Use for hard subproblems, second opinions, code generation/review, or complex synthesis.3 params
Ask a specialist Gateway model for code, database/tool-calling, statistics, literature, preprint, or mechanistic synthesis support. Use for hard subproblems, second opinions, code generation/review, or complex synthesis.
contextstringprompt*stringtask_type*stringcode · database · reasoning · statistics · research · literaturefetchFetch a specific result returned by search. This compatibility tool supports OpenAI and ChatGPT remote MCP retrieval flows.1 params
Fetch a specific result returned by search. This compatibility tool supports OpenAI and ChatGPT remote MCP retrieval flows.
id*stringfetch_research_urlFetch a public HTTPS research URL, JSON API response, package metadata endpoint, documentation page, or dataset preview. Blocks private/internal hosts and truncates large responses.2 params
Fetch a public HTTPS research URL, JSON API response, package metadata endpoint, documentation page, or dataset preview. Blocks private/internal hosts and truncates large responses.
max_chars*numberurl*stringget_claim_contentRetrieve the complete text content of a specific Claidex Claim by its slug. Use this when you need to read the full post-mortem analysis, including hypothesis, failure mechanism, and prevention analysis.1 params
Retrieve the complete text content of a specific Claidex Claim by its slug. Use this when you need to read the full post-mortem analysis, including hypothesis, failure mechanism, and prevention analysis.
slug*stringquery_chemblLook up a drug or compound in ChEMBL. Returns mechanism of action, primary target, ChEMBL ID, max development phase, molecular type, and synonyms.1 params
Look up a drug or compound in ChEMBL. Returns mechanism of action, primary target, ChEMBL ID, max development phase, molecular type, and synonyms.
drug_name*stringquery_clinicaltrialsSearch ClinicalTrials.gov for clinical trials. Can search by drug name, condition, target, or NCT ID. Returns trial status, phase, sponsor, primary endpoints, and why_stopped if terminated.4 params
Search ClinicalTrials.gov for clinical trials. Can search by drug name, condition, target, or NCT ID. Returns trial status, phase, sponsor, primary endpoints, and why_stopped if terminated.
max_results*numberphase*stringPHASE1 · PHASE2 · PHASE3 · PHASE4 · anydefault: anyquery*stringstatus*stringRECRUITING · ACTIVE_NOT_RECRUITING · TERMINATED · WITHDRAWN · COMPLETED · anydefault: anyquery_failure_graphQuery the Claidex failure graph for a specific gene target. Returns the Mechanism Risk Score (MRS), failure counts by phase and archetype, and all related claim slugs.1 params
Query the Claidex failure graph for a specific gene target. Returns the Mechanism Risk Score (MRS), failure counts by phase and archetype, and all related claim slugs.
target_gene*stringquery_openfdaQuery the FDA FAERS database for adverse event signals for a drug. Returns top adverse event terms, serious case count, and death count.2 params
Query the FDA FAERS database for adverse event signals for a drug. Returns top adverse event terms, serious case count, and death count.
drug_name*stringmax_results*numberquery_opentargetsQuery Open Targets for target-disease association evidence. Returns genetic evidence score, clinical evidence, known drugs, tractability, and safety liabilities for a gene-disease pair.2 params
Query Open Targets for target-disease association evidence. Returns genetic evidence score, clinical evidence, known drugs, tractability, and safety liabilities for a gene-disease pair.
disease_term*stringtarget_gene*stringquery_package_registryLook up package metadata from npm or PyPI before recommending code, analysis packages, API clients, or dataset tooling.2 params
Look up package metadata from npm or PyPI before recommending code, analysis packages, API clients, or dataset tooling.
ecosystem*stringnpm · pypipackage_name*stringrank_documents_by_embeddingEmbed a query and candidate documents, then rank documents by cosine similarity. Use for semantic matching, retrieval checks, clustering triage, and lightweight RAG over user-provided passages.3 params
Embed a query and candidate documents, then rank documents by cosine similarity. Use for semantic matching, retrieval checks, clustering triage, and lightweight RAG over user-provided passages.
documents*arrayquery*stringtop_k*numberrerank_documentsRerank candidate documents/passages against a query using a dedicated reranking model. Use after retrieval/search when exact relevance ordering matters.3 params
Rerank candidate documents/passages against a query using a dedicated reranking model. Use after retrieval/search when exact relevance ordering matters.
documents*arrayquery*stringtop_n*numberrun_computationEvaluate deterministic mathematical expressions with optional variables. Use for algebra, matrices, vectors, transformations, descriptive numerical checks, and reproducible calculations. Does not execute arbitrary JavaScript or install packages.2 params
Evaluate deterministic mathematical expressions with optional variables. Use for algebra, matrices, vectors, transformations, descriptive numerical checks, and reproducible calculations. Does not execute arbitrary JavaScript or install packages.
expression*stringvariables*objectrun_statistical_analysisRun a statistical analysis computation. Supports: Wilson confidence intervals, binomial proportions, phase transition success rates, power calculations, Bayesian posterior estimates, descriptive statistics, and two-proportion comparisons. Returns computed values, interpretatio...3 params
Run a statistical analysis computation. Supports: Wilson confidence intervals, binomial proportions, phase transition success rates, power calculations, Bayesian posterior estimates, descriptive statistics, and two-proportion comparisons. Returns computed values, interpretatio...
analysis_type*stringwilson_ci · phase_transition_rate · power_calculation · bayesian_posterior · descriptive_stats · failure_rate_comparisoncontextstringinputs*objectsearchSearch Claidex failure claims and preprint flags. This compatibility tool returns citation-ready results for OpenAI and ChatGPT remote MCP flows.2 params
Search Claidex failure claims and preprint flags. This compatibility tool returns citation-ready results for OpenAI and ChatGPT remote MCP flows.
limit*integerquery*stringsearch_claimsSearch the Claidex failure database for post-mortems matching a drug name, gene target, disease, failure archetype, or sponsor. Returns matching claims with title, slug, drug, target, disease, phase, failure archetype, Open Targets score, and MRS score.4 params
Search the Claidex failure database for post-mortems matching a drug name, gene target, disease, failure archetype, or sponsor. Returns matching claims with title, slug, drug, target, disease, phase, failure archetype, Open Targets score, and MRS score.
category*stringOncology · Cardiology · Neurology · Immunology · Infectious Disease · Metabolicdefault: anyfailure_archetype*stringefficacy_failure · safety_signal · enrollment_collapse · sponsor_decision · strategic_reprioritization · translational_mismatchdefault: anylimit*numberquery*stringsearch_preprint_flagsSearch the Claidex Preprint Watch database for bioRxiv preprints flagged as contradicting the clinical failure record. Search by target gene, disease, or preprint title.2 params
Search the Claidex Preprint Watch database for bioRxiv preprints flagged as contradicting the clinical failure record. Search by target gene, disease, or preprint title.
query*stringseverity*stringSTRONG · MODERATE · MILD · anydefault: anysearch_pubmedSearch PubMed for biomedical literature. Returns title, authors, journal, year, DOI, abstract, and PMID for each result.2 params
Search PubMed for biomedical literature. Returns title, authors, journal, year, DOI, abstract, and PMID for each result.
max_results*numberquery*stringweb_searchSearch the web for recent news, investor commentary, analyst notes, press releases, and conference coverage about drugs, clinical trials, or biomedical mechanisms.2 params
Search the web for recent news, investor commentary, analyst notes, press releases, and conference coverage about drugs, clinical trials, or biomedical mechanisms.
focus*stringnews · academic · investor · anydefault: anyquery*stringSponsors
Configuration
CLAIDEX_MCP_URLdefault: https://app.claidex.com/api/mcpClaidex MCP endpoint URL.
CLAIDEX_MCP_API_KEY*secretClaidex API key for protected tools and resources.
Readme
Details
- Repository
- github.com/ssatanis/claidex-sentinel
- Website
- claidex.com
- Package
@claidex-mcp/claidex-mcp- Transport
- STDIO, HTTP
- Auth
- Required
- Registry
- MCP registry, active
- Resources
- 5
- Prompts
- 5
- Tools verified
- Nov 6, 2026