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Biopharma Catalyst Mcp

yesc97/biopharma-catalyst-mcp

Connects Claude to six free biopharma data sources (ClinicalTrials.gov, PubMed, SEC EDGAR, SEC XBRL, openFDA, Yahoo Finance) and runs forensic audits on drug catalysts. The headline tool is audit_catalyst, which takes a ticker, drug name, and sponsor, then returns a deterministic verdict (CLEAN, FLAG, BEAR_SIGNAL, BLACK_FLAG, or DISQUALIFIED) by cross-referencing trial status, FDA approval history, cash runway, insider transactions, and options IV. Built for the workflow of checking whether a catalyst story holds up. Individual tools let you query each source directly if you want to bypass the aggregator. No API keys required. Designed to compress a 2-4 hour manual research session into 30 seconds by surfacing trial terminations, amended protocols, and cash burn against what the company is saying publicly.

GitHub stars
3
tools
10
auth
Required
transport
STDIO
env var
1
last updated
May 11, 2026

Tools

10 tools

Public tool metadata for what this MCP can expose to an agent.

audit_catalystHeadline tool. Runs the full Tactical Auditor workflow against (ticker, drug). Deterministic verdict.

Headline tool. Runs the full Tactical Auditor workflow against (ticker, drug). Deterministic verdict.

No parameter schema in public metadata yet.

search_clinical_trialsPipeline + status by intervention; flags terminations, withdrawals, completed-without-readout

Pipeline + status by intervention; flags terminations, withdrawals, completed-without-readout

No parameter schema in public metadata yet.

search_pubmedRecent literature on a drug / mechanism / disease

Recent literature on a drug / mechanism / disease

No parameter schema in public metadata yet.

get_sec_filingsLast 10 filings (10-K, 10-Q, 8-K, S-1) by ticker

Last 10 filings (10-K, 10-Q, 8-K, S-1) by ticker

No parameter schema in public metadata yet.

get_xbrl_factsCash, quarterly burn, runway months, Going Concern flag

Cash, quarterly burn, runway months, Going Concern flag

No parameter schema in public metadata yet.

get_insider_transactionsRole-classified insider transactions (clinical/financial/admin), coordinated exit detection (72h window), Net Insider Sentiment ($), 10b5-1 detection

Role-classified insider transactions (clinical/financial/admin), coordinated exit detection (72h window), Net Insider Sentiment ($), 10b5-1 detection

No parameter schema in public metadata yet.

get_short_interestShort % of float, days to cover, MoM delta — feeds SHORT_INTEREST_SPIKE and SHORT_SQUEEZE_POTENTIAL signals

Short % of float, days to cover, MoM delta — feeds SHORT_INTEREST_SPIKE and SHORT_SQUEEZE_POTENTIAL signals

No parameter schema in public metadata yet.

get_protocol_snapshotTrial protocol + amendment proximity (goalpost detection)

Trial protocol + amendment proximity (goalpost detection)

No parameter schema in public metadata yet.

get_market_dataQuote + full options chain (IV, strikes, expirations)

Quote + full options chain (IV, strikes, expirations)

No parameter schema in public metadata yet.

get_fda_activityNDA/BLA submissions with decoded status (AP, CRL, WD, etc.); auto-fallback drug→sponsor

NDA/BLA submissions with decoded status (AP, CRL, WD, etc.); auto-fallback drug→sponsor

No parameter schema in public metadata yet.

Sponsors

Configuration

SEC_USER_AGENT*

SEC EDGAR User-Agent header (your-app/1.0 your@email.com). Required by SEC fair-use policy.

Readme

biopharma-catalyst-mcp

License: ISC CI

A forensic biopharma research MCP server — pulls catalyst-grade signals from 6 free, authoritative sources (ClinicalTrials.gov, PubMed, SEC EDGAR, SEC XBRL companyfacts, openFDA, Yahoo Finance) and hands them to your LLM. Includes a server-side aggregator that runs the full forensic workflow in one tool call and returns a deterministic verdict.

Built for the workflow most retail biopharma analysts actually run: a ticker hits the radar, you spend 2–4 hours grinding Google Scholar, FDA pages, EDGAR, and the options chain to decide if the catalyst story holds up. This compresses that to ~30 seconds.


View the full README on GitHub

Details

Repository
github.com/yesc97/biopharma-catalyst-mcp
Package
biopharma-catalyst-mcp
Transport
STDIO
Auth
Required
Registry
MCP registry, active