Clinpgx Database

This connects you to the ClinPGx API, the successor to PharmGKB that consolidates pharmacogenomics data for clinical decision support. Query gene-drug interactions (like CYP2D6 and codeine), pull CPIC guidelines with phenotype-specific dosing recommendations, and look up allele functions across populations. The API is straightforward REST calls with no auth required, though watch the 2 requests per second rate limit. Most valuable when you're building precision medicine tools or need to programmatically check if a patient's genotype affects drug metabolism, efficacy, or toxicity risk. Covers the major pharmacogenes (CYP450s, TPMT, DPYD, HLA variants) and includes evidence levels so you know what's guideline-backed versus preliminary.

skills.sh installs: 261
GitHub stars: 33.2K
last updated: Aug 21, 2026

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Install

$ npx -y skills add davila7/claude-code-templates --skill clinpgx-database --agent claude-code

Installs into .claude/skills of the current project.

Files

ClinPGx Database

Overview

ClinPGx (Clinical Pharmacogenomics Database) is a comprehensive resource for clinical pharmacogenomics information, successor to PharmGKB. It consolidates data from PharmGKB, CPIC, and PharmCAT, providing curated information on how genetic variation affects medication response. Access gene-drug pairs, clinical guidelines, allele functions, and drug labels for precision medicine applications.