Brenda Database

If you're doing biochemical research or metabolic engineering and need enzyme data, this gives you programmatic access to BRENDA, the most comprehensive enzyme database out there. You can query kinetic parameters like Km and kcat values, pull reaction equations, compare enzyme properties across organisms, and find enzymes for specific substrates or transformations. It uses the official SOAP API to access millions of data points covering 45,000+ enzymes. The real value is in the substrate specificity comparisons and organism-specific data, which saves you from manually parsing literature when you're trying to find the right enzyme variant or optimize reaction conditions. Solid tool if you're building metabolic pathways or doing enzyme discovery work.

skills.sh installs: 222
GitHub stars: 33.2K
last updated: Aug 21, 2026

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Install

$ npx -y skills add davila7/claude-code-templates --skill brenda-database --agent claude-code

Installs into .claude/skills of the current project.

Files

BRENDA Database

Overview

BRENDA (BRaunschweig ENzyme DAtabase) is the world's most comprehensive enzyme information system, containing detailed enzyme data from scientific literature. Query kinetic parameters (Km, kcat), reaction equations, substrate specificities, organism information, and optimal conditions for enzymes using the official SOAP API. Access over 45,000 enzymes with millions of kinetic data points for biochemical research, metabolic engineering, and enzyme discovery.