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Tooluniverse Clinical Guidelines

Pulls clinical practice guidelines from NICE, WHO, NCCN, AHA, ADA, SIGN, USPSTF, and about a dozen other authoritative sources. The skill knows to prioritize evidence-graded sources like NICE and WHO over society consensus guidelines, always checks publication dates since guidelines age fast, and searches at least three databases in parallel to avoid missing updates. It includes solid decision frameworks for diagnostic test selection (sensitivity vs specificity, screening vs confirmation) and explains how to apply population-level guidelines to individual patients. The compute-first approach means it actually runs analysis code instead of describing what it would do. Useful when you need current treatment protocols, screening criteria, or dosing guidance backed by named sources rather than model-generated suggestions.

skills.sh installs
496
GitHub stars
1.8K
last updated
Aug 21, 2026

Install

$ npx -y skills add mims-harvard/tooluniverse --skill tooluniverse-clinical-guidelines --agent claude-code

Installs into .claude/skills of the current project.

Files

Clinical Guidelines Search & Retrieval

Guideline Hierarchy

Not all guidelines carry equal weight. Evaluate sources in this order:

  1. NICE and WHO — Evidence-graded, regularly updated, rigorous systematic review process. NICE guidelines include explicit recommendation strength (e.g., "offer" vs "consider").
  2. Society guidelines (AHA, ADA, NCCN, SIGN) — Expert-consensus panels within a specialty. May lag behind the latest evidence by 1-3 years. Strong within their domain but narrower scope.
  3. Aggregator databases (TRIP, OpenAlex) — Index guidelines from multiple societies. Good for breadth and discovery, but you must verify the original source.
  4. Literature databases (PubMed, EuropePMC) — Return guideline-related publications, not curated guideline text. Useful as a fallback, not a primary source.

Always check publication date. A 2015 guideline may be superseded by a 2024 update. When presenting results, include the year prominently and note if newer guidance may exist.


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Details

Repository
github.com/mims-harvard/tooluniverse
First seen
Jun 3, 2026

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