Gtars

If you're doing computational genomics work and need to wrangle BED files, detect overlaps, or generate coverage tracks, this is a Rust-based toolkit with Python bindings that handles the performance-critical parts of your pipeline. It's built around specialized modules: IGD indexing for overlap queries, uniwig for coverage tracks, tokenizers for ML preprocessing, and reference sequence management following GA4GH refget. The real value is when you're preprocessing genomic intervals for machine learning models or need fast fragment analysis in single-cell ATAC-seq data. It underpins the geniml package, so if you're in that ecosystem you're already depending on it. The CLI handles one-off tasks well, but the Python API is where you'll spend time for custom workflows.

skills.sh installs: 210
GitHub stars: 33.2K
last updated: Aug 21, 2026

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Install

$ npx -y skills add davila7/claude-code-templates --skill gtars --agent claude-code

Installs into .claude/skills of the current project.

Files

Gtars: Genomic Tools and Algorithms in Rust

Overview

Gtars is a high-performance Rust toolkit for manipulating, analyzing, and processing genomic interval data. It provides specialized tools for overlap detection, coverage analysis, tokenization for machine learning, and reference sequence management.

Use this skill when working with:

Genomic interval files (BED format)
Overlap detection between genomic regions
Coverage track generation (WIG, BigWig)
Genomic ML preprocessing and tokenization
Fragment analysis in single-cell genomics
Reference sequence retrieval and validation

Installation

Python Installation

Install gtars Python bindings:

uv uv pip install gtars

CLI Installation

Install command-line tools (requires Rust/Cargo):

# Install with all features
cargo install gtars-cli --features "uniwig overlaprs igd bbcache scoring fragsplit"

# Or install specific features only
cargo install gtars-cli --features "uniwig overlaprs"

Rust Library

Add to Cargo.toml for Rust projects:

[dependencies]
gtars = { version = "0.1", features = ["tokenizers", "overlaprs"] }

Core Capabilities

SKILL.md on GitHub

Details

Repository: github.com/davila7/claude-code-templates
Categories: Testing & QA, Data Science & ML, Debugging, Python, Rust
First seen: Jun 3, 2026