Interpro Database

This gives Claude Code access to InterPro, the protein sequence analysis database that consolidates signatures from Pfam, CDD, SMART, and other member databases into one searchable resource. You'd reach for this when working on bioinformatics tasks that involve identifying protein families, domains, or functional sites. It's part of Google DeepMind's science-skills collection and has passed security audits from multiple providers. Worth noting that it requires uv to be installed and will prompt you to review EBI's terms of use on first run. The 958 installs suggest a solid niche audience, which makes sense given how specialized protein database work tends to be.

skills.sh installs: 2.2K
GitHub stars: 3.4K
last updated: Aug 21, 2026

View on GitHub

Install

$ npx -y skills add google-deepmind/science-skills --skill interpro-database --agent claude-code

Installs into .claude/skills of the current project.

Files

InterPro Database Access

Prerequisites

uv: Read the uv skill and follow its Setup instructions to ensure uv is installed and on PATH.
User Notification: If .licenses/interpro_database_LICENSE.txt does not already exist in the workspace root directory then (1) prominently notify the user to check the terms at https://www.ebi.ac.uk/interpro/ and https://www.ebi.ac.uk/about/terms-of-use/, then (2) create the file recording the notification text and timestamp.

Overview

InterPro combines signatures from multiple, diverse databases into a single searchable resource, reducing redundancy and helping users interpret their sequence analysis results. By uniting these member databases (e.g., Pfam, CDD, SMART), InterPro capitalises on their individual strengths to produce a powerful diagnostic tool and integrated resource.

Use interpro-database to:

SKILL.md on GitHub