Gtex Database

Pulls transcriptomics data and eQTLs from the GTEx Portal API V2, giving you median TPM values for genes and variant associations across 54 human tissue sites. Built by Google DeepMind as part of their science-skills collection. You'll want this if you're doing genetic research or building tools that need access to baseline RNA expression data without scraping or managing your own GTEx datasets. Requires uv to be installed, and you'll need to acknowledge GTEx's terms of use on first run. It's a straightforward API wrapper, but it saves you from dealing with the portal's documentation yourself. The repo has 2.4K stars and passed security audits from three different tools.

skills.sh installs: 2.2K
GitHub stars: 3.4K
last updated: Aug 21, 2026

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Install

$ npx -y skills add google-deepmind/science-skills --skill gtex-database --agent claude-code

Installs into .claude/skills of the current project.

Files

GTEx Database Integration

This skill retrieves transcriptomics data (RNA expression baselines) and expression Quantitative Trait Loci (eQTLs) from the GTEx Portal API V2. It provides access to median TPM (Transcripts Per Million) values for genes and significant eQTLs for variants across 54 human tissue sites.

Prerequisites

uv: Read the uv skill and follow its Setup instructions to ensure uv is installed and on PATH.
User Notification: If .licenses/gtex_database_LICENSE.txt does not already exist in the workspace root directory then (1) prominently notify the user to check the terms at https://gtexportal.org/home/license and https://gtexportal.org/home/documentationPage#gtexApi, then (2) create the file recording the notification text and timestamp.