Alphagenome Single Variant Analysis
This connects Claude to DeepMind's AlphaGenome API for analyzing genetic variants. You'll need to grab an API key from their site, and the skill handles credentials safely through a dedicated protocol. It's part of DeepMind's broader science-skills collection, which explains the 2.4K stars and relatively high install count. The licensing setup is interesting: it actually creates a timestamped file in your workspace to confirm you've checked their terms before running analysis. If you're working with genomic data and want to tap into AlphaGenome's variant analysis without building your own integration, this gets you there quickly. Requires uv for Python environment management.
- skills.sh installs
- 2.3K
- GitHub stars
- 3.4K
- last updated
- Aug 21, 2026
Install
$ npx -y skills add google-deepmind/science-skills --skill alphagenome-single-variant-analysis --agent claude-codeInstalls into .claude/skills of the current project.
Files
Variant Analysis using AlphaGenome
Prerequisites
-
uv: Read theuvskill and follow its Setup instructions to ensureuvis installed and on PATH. -
User Notification: If .licenses/alphagenome_single_variant_analysis_LICENSE.txt does not already exist in the workspace root directory then (1) prominently notify the user to check the terms at https://deepmind.google.com/science/alphagenome/, then (2) create the file recording the notification text and timestamp.
-
.envfile: Make sure the.envfile exists in your home directory. Create one if it does not exist. -
ALPHAGENOME_API_KEY: This skill requires an API key to function.You can register for a key at https://deepmind.google.com/science/alphagenome/. You MUST use the safe credentials protocol in the
credentialsskill to check for and request this key if this skill looks relevant to the user's request. -
ALPHAGENOME_GTF_PATH(Optional): Accelerate gene/transcript lookup by pointing to a local copy of the GTF feather file instead of downloading from GCS:
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- Repository
- github.com/google-deepmind/science-skills
- Categories
- Backend & APIs, Code Review & Quality, Design & UI/UX
- First seen
- Jul 14, 2026
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