Uniprot Database

Gives Claude direct access to UniProt's protein databases including UniProtKB, UniParc, and UniRef for retrieving curated biological data and running sequence lookups. Comes from DeepMind's science-skills collection and requires uv to be installed. It handles license notifications automatically by checking UniProt's terms and creating a local record in your workspace. This is straightforward infrastructure for bioinformatics work. If you're building anything that needs protein data or cross-referencing biological sequences, this beats writing your own API wrapper. The 980 installs and clean security audits suggest it's a solid implementation from a team that actually uses this stuff.

skills.sh installs: 2.3K
GitHub stars: 3.4K
last updated: Aug 21, 2026

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Install

$ npx -y skills add google-deepmind/science-skills --skill uniprot-database --agent claude-code

Installs into .claude/skills of the current project.

Files

UniProt Database Access

Prerequisites

uv: Read the uv skill and follow its Setup instructions to ensure uv is installed and on PATH.
User Notification: If .licenses/uniprot_database_LICENSE.txt does not already exist in the workspace root directory then (1) prominently notify the user to check the terms at https://www.uniprot.org/help/license and https://www.uniprot.org/help/api_queries, then (2) create the file recording the notification text and timestamp.

Overview

Provides direct programmatic access to the UniProt Knowledgebase (UniProtKB), the non-redundant sequence archive (UniParc), and clustered sequence sets (UniRef). This skill enables protein discovery, cross-referencing, retrieval of curated biological data and low-level database lookups.