Opentargets Database

A GraphQL interface to the Open Targets Platform, which is basically a giant database linking diseases to potential drug targets using evidence from genetics studies, clinical trials, animal models, and pathway data. You'd reach for this when doing early stage drug discovery research or trying to validate whether a gene is worth pursuing as a therapeutic target. The skill handles the API calls and comes from DeepMind's science toolkit, which gives it some credibility. One thing to watch: it requires uv for Python environment management and makes you acknowledge their data license terms before use, so there's a bit of setup friction before you can start querying.

skills.sh installs: 2.3K
GitHub stars: 3.4K
last updated: Aug 21, 2026

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Install

$ npx -y skills add google-deepmind/science-skills --skill opentargets-database --agent claude-code

Installs into .claude/skills of the current project.

Files

Open Targets Database Skill

Overview

This skill provides access to the Open Targets Platform GraphQL API. It aggregates multi-modal evidence from genetics (GWAS/eQTL), pathways, animal models, and clinical trials to rank target-disease associations and identify druggable genes.

Prerequisites

uv: Read the uv skill and follow its Setup instructions to ensure uv is installed and on PATH.
User Notification: If .licenses/opentargets_database_LICENSE.txt does not already exist in the workspace root directory then (1) prominently notify the user to check the terms at https://platform-docs.opentargets.org/licence, then (2) create the file recording the notification text and timestamp.